ea0034p375 | Steroids | SFEBES2014
Kearney Louise
, Gibbs Julie
, Farrow Stuart
, Ray David
, Loudon Andrew
One in five people in the UK is affected by lung disease, along with millions more worldwide. Glucocorticoids represent the most utilized anti-inflammatory therapy for the treatment of pulmonary inflammation, however a subset of patients exist which do not respond to therapeutically relevant doses.The non-ciliated bronchial epithelial (Clara) cells have been identified as key mediators of the pulmonary inflammatory response. The glucocorticoid receptor (...